Citation
Crawford, M.J., Sanatinia, R., Barrett, B., Byford, S., Cunningham, G., Gakhal, K., Lawrence-Smith, G., Leeson, V., Lemonsky, F., Lykomitrou, G. and Montgomery, A., 2015. Lamotrigine versus inert placebo in the treatment of borderline personality disorder: study protocol for a randomized controlled trial and economic evaluation. Trials, 16(1), p.308.
Abstract
People with borderline personality disorder (BPD) experience rapid and distressing changes in mood, poor social functioning and have high rates of suicidal behaviour. Several small scale studies suggest that mood stabilizers may produce short-term reductions in symptoms of BPD, but have not been large enough to fully examine clinical and cost-effectiveness.