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Evaluating cross-regional implementation of interventions to reduce the burden of multiple long-term conditions

Lead: NIHR ARC East Midlands

Why the research is needed?

Implementation and roll-out of interventions in the context of multi-morbidity brings particular challenges due to the multiple healthcare professionals involved, and the complexity and diversity of the patient group.

What we will do?

This project will examine the roll out and implementation processes of the four funded projects as part of the NIHR ARC National MLTC Implementation programme.

We will use a theory-driven valuation approach, treating each of the projects as a case study to explore implementation approaches and factors impacting large scale implementation of interventions in each project. We will work with the teams to identify cross-project learning.

This will involve secondary analysis of quantitative and qualitative data on implementation processes and outcomes from the four projects, as well as primary data collection involving longitudinal interviews with project leads and stakeholders, and stakeholder workshops.

What will be achieved?

This project will undertake comparative, cross-case analysis to generate higher-level learning from across the four projects about the challenges and facilitators of large-scale implementation in the context of MLTC. The project will use the CFIR framework, and Normalisation Process Theory to help us to identify contextual factors and mechanisms that promote successful implementation and roll out. Specifically, the objectives of this evaluation will be to determine (i) what processes worked, where and why, and (ii) what factors impact on the large scale-implementation of interventions to address the burden of multiple long-term conditions.

When the findings will be available? 

April 2024

Contribution to National Priority Aims:

Understanding of important contextual factors and mechanisms explaining the process of implementation in cross-regional interventions to tackle MLTC.

Contact: Carolyn Tarrant,