What we are doing:
We are using the UK Biobank dataset, which is one of the world’s largest Biobank cohorts designed to improve the prevention and treatment of long-term diseases. With access to the database, we are able to extract data from people with multimorbidity and compare the characteristics, physical activity levels and other lifestyle behaviours to those without multimorbidity. Also, using the latest survival modelling techniques, we are developing a statistical programme that is able to estimate life expectancy.
Why we are doing it:
Multimorbidity, known as someone having two or more long-term conditions, has dramatically increased across the globe and has become a major priority for public healthcare systems as they are currently designed to treat only single diseases. Very few studies have examined effective interventions that improve outcomes such as mortality and life expectancy, in particular lifestyle behaviours which are modifiable can bring significant benefits to both the patients and public healthcare providers. Therefore, this PhD project aims to explore the role of physical activity and other lifestyle behaviours in the association between multimorbidity and life expectancy.
What the benefits will be:
Approaching multimorbidity as a whole has significant benefits since we are able to reflect the reality of patients today instead of focusing on individual diseases. Additionally, developing the programme and exploring life expectancy by modifiable lifestyle behaviours will provide a much stronger and clearer message, and will better inform patients with multimorbidity and public healthcare systems.
Who we are working with:
- Leicester Clinical Trials Unit
- NIHR Leicester Biomedical Research Centre
Yogini Chudasama, PhD Student in Epidemiology